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The study is conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Ethics Committee of the Medical University of Bialystok (Project identification code: R-I-002/546/2015)

Visible improvements appear within a few weeks, with optimal results developing over 3 months

however, the procedure is unable to restore the intervertebral space height or maintain the stability of the intervertebral space

f, g and h , Bars represent mean s.d

Recurrent hypoglycemia necessitates medication regimen review and adjustment

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